Description
Diltiazem hydrochloride, a calcium channel blocker, can be used for treating anal fissures by lowering anal sphincter pressure(smooth muscle around the rectum), and also promotes wound healing and treat external thrombosed hemorrhoids. The use of topical 2% diltiazem hydrochloride for treating anal fissures is supported by multiple clinical trials. There no commercially manufactured formulation of topical 2% diltiazem has been approved yet by the Food and Drug Administration for the treatment of anal fissure, prescriptions for the medication need to be compounded with a prescription from a doctor.

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